The largest study to date on the genetics of glaucoma has identified 2 genetic variations that are associated with the condition.
Over 6000 patients, half of whom had primary open angle glaucoma had their DNA analysed. Variations were found in 2 genes which may interact with transforming growth factor beta (TGF-beta), a molecule that regulates cell growth and survival throughout the body. Other genetic research into glaucoma have also pointed to a role in glaucoma for TGF-beta.
The researchers hope that by finding the genes responsible for the condition, new genetic based preventions and treatments can be found. Glaucoma is a leading cause of blindness worldwide and affects around 2% of people over 40. If you have a family history or are concerned about the condition make sure you come and see us.